machine
1 [intransitive] + adverb/preposition to work in a particular waySynonym
functionMost domestic freezers operate at below −18 °C.Solar panels can only operate in sunlight. (figurative) Some people can only operate well under pressure.
2 [transitive] operate something to use or control a machine or make it workWhat skills are needed to operate this machinery?system/process/service
3 [intransitive, transitive] to be used or working; to use something or make it workA new late-night service is now operating.The regulation operates in favour of married couples.operate something The airline operates flights to 25 countries.France operates a system of subsidized loans to dairy farmers.of business/organization
4 [intransitive] + adverb/preposition to work in a particular way or from a particular placeThey plan to operate from a new office in Edinburgh.Illegal drinking clubs continue to operate in the city.medical
5 [intransitive] to cut open somebody's body in order to remove a part that has a disease or to repair a part that is damagedThe doctors operated last night.operate (on somebody) (for something) We will have to operate on his eyes.to operate for suspected acute appendicitis

ˈɒpəreɪt
ˈɑːpəreɪt